Flaxseed oil reduces the growth of human breast tumors (MCF-7) at high levels of circulating estrogen.

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Flaxseed Ingestion Alters Ratio of Enterolactone Enantiomers in Human Serum.

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Tamoxifen, flaxseed and the lignan enterolactone increase stroma and cancer cell derived IL-1Ra and decrease tumor angiogenesis in estrogen dependent breast cancer .

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Dietary flaxseed lignan or oil combined with tamoxifen treatment affects MCF-7 tumor growth through estrogen.

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Role of dietary fatty acids in mammary gland development and breast cancer.

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Lignans and breast cancer risk in pre- and post-menopausal women: meta-analyses of observational studies.

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The relation of a-linolenic acid to the risk of prostate cancer: a systematic review and meta-analysis.

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Dietary lignans and postmenopausal breast cancer risk by oestrogen receptor status: a prospective cohort study of Swedish women.

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Changes in biomarkers of estrogen receptor and growth factor signaling pathways in MCF-7 tumors after short- and long-term treatment with soy and flaxseed.

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Overcoming challenges in designing and implementing a phase II randomized controlled trial using a presurgical model to test a dietary intervention in prostate cancer.

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