Conversion of Alpha Linolenic Acid to Longer-Chain Omega 3 Fatty Acids

Essential fatty acids (EFAs) are required in the diet as they can not be synthesized by humans from the shorter chain fatty acid, oleic acid (C18:1). The omega-6 fatty acid linoleic acid (C18:2n-6, LA) found in many vegetable oils such as soy and corn oils, and the omega-3 fatty acid alpha-linolenic (C18:3n-3, ALA) are EFAs.  Read More

Maternal polymorphisms in the FADS1 and FADS2 genes modify the association between PUFA ingestion and plasma concentrations of omega-3 polyunsaturated fatty acids.

Sex hormones and n-3 fatty acid metabolism.

Effect of one and two months high dose alpha-linolenic acid treatment on 13 C-labeled alpha-linolenic acid incorporation and conversion in healthy subjects.

Effects of a low and a high dietary LA/ALA ratio on long-chain PUFA concentrations in red blood cells.

Effect of supplementation with flaxseed oil and different doses of fish oil for 2 weeks on plasma phosphatidylcholine fatty acids in young women.

Dietary linoleic acid and sex effects on oxylipin profiles in rat kidney, liver and serum differ from their effects on polyunsaturated fatty acids.

Effects of a hypoenergetic diet rich in α-linolenic acid on fatty acid composition of serum phospholipids in overweight and obese patients with metabolic syndrome.

Preliminary evaluation of a differential effect of an a-linolenate-rich supplement on ketogenesis and plasma n-3 fatty acids in young and older adults

The effect of linoleic acid on the whole body synthesis rates of polyunsaturated fatty acids from α-linolenic acid and linoleic acid in free-living rats.