Comb Chem High Throughput Screen., 2024, 2024 May 22. doi: 10.2174/0113862073316439240515072946

Lignans: Advances in Biosynthesis, Bioavailability, and Pharmacological Activity

Singh S Sharma S

Lignans, a group of naturally occurring compounds abundant in various plant-based foods, are
becoming increasingly popular due to their potential health benefits. The literature suggests that
these bioactive substances can reduce the risk of certain types of cancer, such as
postmenopausal colon and breast cancer. Moreover, the significance of lignans for improving
cardiovascular health has been recognized, as studies have revealed a potential correlation
between the intake of lignans and a decreased risk of cardiovascular disease. These complex
molecules possess diverse bioactive capabilities, rendering them potential alternatives for
preventing chronic diseases. Further research is needed to examine the mechanisms
responsible for their beneficial outcomes. Recent research has emphasized the
pharmacological properties of lignans as effective substances for human health. Incorporating
foods rich in lignans into the diet may be a practical approach to enhancing protection against
life-threatening ailments, such as cardiovascular diseases and malignancies.

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