Meta-analysis supports α-Linolenic acid Intake and Reduced Coronary Heart Disease

Flaxseed provides a unique mix of fatty acids. It is low in saturates (less than 9% of total fatty acids) and contains the essential polyunsaturated fatty acids omega-3 α-linolenic acid (ALA; 18:3n-3) and omega-6 linoleic acid (LA; 18:2n-6). Essential fatty acids are required in the diet as they cannot be made by humans. Most notably, Read More

Anticancer potentiality of lignan rich fraction of six Flaxseed cultivars.

An altered tissue distribution of flaxseed lignans and their metabolites in Abcg2 knockout mice.

Flaxseed Lignans Enhance the Cytotoxicity of Chemotherapeutic Agents against Breast Cancer Cell Lines MDA-MB-231 and SKBR3.

Omega-3 Polyunsaturated Fatty Acids Time-Dependently Reduce Cell Viability and Oncogenic MicroRNA-21 Expression in Estrogen Receptor-Positive Breast Cancer Cells (MCF-7).

The association and dose-response relationship between dietary intake of α-linolenic acid and risk of CHD: a systematic review and meta-analysis of cohort studies.

Key findings This meta-analysis examined an aggregate association between ALA intake and risk of CHD, and assessed any dose-response relationships. The investigators searched the PubMed, EMBASE and Web of Science databases over a 50-year period (from January 1966 to August 2017) that investigated the associations between dietary ALA intake and CHD. They included original full-text Read More

Safflower (n-6) and flaxseed (n-3) high-fat diets differentially regulate hypothalamic fatty acid profiles, gene expression, and insulin signalling.

Secoisolariciresinol diglucoside is a blood-brain barrier protective and anti-inflammatory agent: implications for neuroinflammation.

Marine fish oil is more potent than plant-based n-3 polyunsaturated fatty acids in the prevention of mammary tumors.

Antidepressant-Like Effect of Selected Egyptian Cultivars of Flaxseed Oil on a Rodent Model of Postpartum Depression.