Key Findings:
This comprehensive review provides background information describing the effects of whole milled flaxseed and its constituents (oil, fiber and lignans) on a number of clinical outcomes. Research is profiled that shows the various levels of efficacious effects of flaxseed in Myocardial infarction, morbidity and mortality; stroke; high blood cholesterol and other lipids; high blood pressure; inflammatory biomarkers; diabetes; menopause symptoms and stress. The reader is encouraged to download this extensive and well referenced review.
ABSTRACT:
Preventing the occurrence of cardiovascular disease (CVD) with nutritional interventions is a therapeutic strategy that may warrant greater research attention. The increased use of omega-3 fatty acids is a powerful example of one such nutritional strategy that may produce significant cardiovascular benefits. Marine food products have provided the traditional dietary sources of omega-3 fatty acids. Flaxseed is an alternative to marine products. It is one of the richest sources of the plant-based omega-3 fatty acid, alpha-linolenic acid (ALA). Based on the results of clinical trials, epidemiological investigations and experimental studies, ingestion of ALA has been suggested to have a positive impact on CVD. Because of its high ALA content, the use of flaxseed has been advocated to combat CVD. The purpose of the present review was to identify the known cardiovascular effects of flaxseed and ALA and, just as importantly, what is presently unknown. (Authors Abstract)